NEWS

---

ABSSeq 1.35.2 (2018-06-28)

• Updating! Extend aFold to paired samples

ABSSeq 1.32.2 (2017-12-18)

• Updating! Refine qtotal (R funtion: qtotalNormalized)

ABSSeq 1.30.1 (2017-07-18)

• Updating! Adapt aFold model for complex design with linear model (R funtion: ABSSeqlm)
• Updating! Introduce a new approach for normalization as qtotal (R funtion: qtotalNormalized)
• aFold now moderates fold changes upon overall dispersion and gene-specific dispersion

ABSSeq 1.11.0 (2017-02-14)

• Updating! Adding new method: aFold to call DE via fold-change

ABSSeq 1.6.0 (2016-02-29)

• Updating! Enable the paired comparison by seting up 'paired' parameter in 'ABSDataSet' object

ABSSeq 1.5.1 (2015-08-24)

• This is the second version of ABSSeq. o Use NB distribution insead of GP to model the counts difference between conditions o Introduce an efficient outlier detection method: moderated MAD o Introduce penalty for dispersion estimation o Provide moderation of log2 fold-change at expression level and gene-specific dispersion